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학술논문

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위・아래 삭제 복제 복제전송 텍스트기본스타일
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CASE REPORT
학술논문

TCBio Japan Cooperation Hospital
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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CASE REPORT
학술논문

TCBio Japan Cooperation Hospital
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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수지상세포 학술논문

많은 의사들이 보다 더 좋은 치료 결과를 만들기 위해 치료 효과를 분석하고 연구에 매진하고 있습니다.
수지상세포를 이용한 암 백신요법은 전 세계 많은 연구진에 의해 연구되어 온 과학적이고 검증된 암 치료법입니다.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 위암/식도암/대장암 Stomach/Esophageal/Colon Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Chang AE, et al(2002), A Phase I Trial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer, Clin Cancer Res, (4) :1021-32.
Fong L, et al(2001), Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy, Proc Natl Acad Sci US A, ; 98 (15) :8809-14.
Homma S, et al(2005), Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12. Clin Cancer Res, ; 11 (8) :3017-24.
Itoh T, et al(2002), Immunotherapy of solid cancer using dendritic cells pulsed with the HLA-A24-restricted peptide of carcinoembryonic antigen, Cancer Immunol Immunother, (2) :99-106.
Kono K, et al(2002), Dendritic cells pulsed with Her-2/neu-derived peptides can induce specific T-cell responses in patients with gastric cancer, Clin Cancer Res, (11) :3394-400.
Liu KJ, et al(2004), Generation of carcinoembryonic antigen (CEA)-specific T-cell response in HLA-A0201 and HLA-A2402 late-stage colorectal cancer patients after vaccination with dendritic cells loaded with CEA peptides, Clin Cancer Res, (8) :2645-51.
Loveland BE, et al(2005), Mannan-MUC1-pulsed dendritic cell immunotherapy : A phase I trial in patients with adenocarcinoma, Anticancer Res, (6A) :3771-6.
Mazzolini G, et al(2005), Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas, J Clin Oncol, (5) :999-1010.
Morse MA, et al(2005), Phase I study of immunization with dendritic cells modified with fowlpox encoding carcinoembryonic antigen and costimulatory molecules, Clin Cancer Res, (8) :3017-24.
Morse M, et al(2003), Immunotherapy with autologous, human dendritic cells transfected with carcinoembryonic antigen mRNA, Cancer Investigation, (3) : 341-349.
Morse M, et al(1999), A phase 1 study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen, Clin Cancer Res, (6) :1331-8.
Sakakibara M, et al(2011), Comprehensive immunological analyses of colorectal cancer patients in the phase I / II study of quickly matured dendritic cell vaccine pulsed with carcinoembryonic antigen peptide, Cancer Immunol Immunother
Sadanaga N, et al(2001), Dendritic cell vaccination with mage peptide is a novel therapeutic approach for gastrointestinal carcinomas, Clin Cancer Res, (8) :2277-84.
Toungouz M, et al(2001), Transient expansion of peptide-specific lymphocytes producing IFN-gamma after vaccination with dendritic cells pulsed with MAGE peptides in patients with mage-A1/A3-positive tumors. J Leukoc Biol, (6) :937-43.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 두경부암 Head and Neck Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Lin C, et al(2002), Immunization with Epstein-Barr Virus (EBV) peptide-pulsed dendritic cells induces functional CD8 + T-cell immunity and may lead to tumour regression in patients with EBV-positive nasopharyngeal carcinoma, Cancer Res, (23) :6952-8.
Toungouz M, et al(2001), Transient expansion of peptide-specific lymphocytes producing IFN-gamma after vaccination with dendritic cells pulsed with MAGE peptides in patients with mage-A1/A3-positive tumors, J Leukoc Biol, (6) :937-43.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 뇌종양 Brain Tumor
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Caruso DA, et al(2004), Results of a phase 1 study utilizing monocyte-derived dendritic cells pulsed with tumor RNA in children and young adults with brain cancer, Neuro Oncol, (3) :236-46.
Chang CN.et.al(2011), A Phase I / II clinical trial investigating the adverse and therapeutic effects of a postoperative autologous dendritic cell tumor vaccine in patients with malignant glioma, J Clin Neurosci, (8) :1048-54.
Chang AE, et al(2002), A Phase I Trial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer, Clin Cancer Res, (4) :1021-32.
Homma S, et al(2005), Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12, Eur J Clin Invest, (4) :279-86.
John H.Sampson.et.al(2009), An epidermal growth factor receptor variant III-targeted vaccine is safe and immunogenic in patients with glioblastoma multiforme, Mol Cancer Ther, (10) :2773-9.
Khan JA et al(2006), Dendritic cell therapy with improved outcome in glioma multiforme - a case report. J Zhejiang Univ Sci B, (2) :114-7.
Kikuchi T, et al(2001), Results of a phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells, Cancer Immunol Immunother, (7) :337-44.
Kikuchi T, et al(2004), Vaccination of glioma patients with fusions of dendritic and glioma cells and recombinant human interleukin 12, J Immunother, (6) :452-9.
Liau LM, et al(2005), Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironment, Clin Cancer Res, (15) :5515-25.
Mayordomo JI, et al(2007), Results of a pilot trial of immunotherapy with dendritic cells pulsed w ith autologous tumor lysates in patients with advanced cancer, Tumori, (1) :26-30.
Steven De Vleeschouwer, et al(2008), prostoperative Ajuvant Dentritic cell-based Immunotherapy In patients with Relapsed Glioblastomo Multiforme, Clin Cancer Res, (10) May3098-3104. Walker DG.et al(2008), Results of phase 1dendritic cell vaccines trial for malignant astrocytoma : potential interaction with ajuvant chemotherapy, J Clin Neurosci, (2) :114-21.
Yamanaka R, et al(2003), Vaccination of recurrent glioma patients with tumour lysate-pulsed dendritic cells elicits immune responses : results of a clinical phase I / II trial, Br J Cancer, (7) :1172-9.
Yamanaka R, et al(2005), Clinical evaluation of dendritic cell vaccination for patients with recurrent glioma : results of a clinical phase I / II trial, Clin Cancer Res ,(11) :4160-7.
Yu JS, et al(2001), Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltration, Cancer Res, 61 (3) :842-7.
Yu JS, et al(2004), Vaccination with tumour lysate-pulsed dendritic cells elicits antigen-specific, cytotoxic T-cells in patients with malignant glioma, Cancer Res, (14) :4973-9.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 췌장암/담낭암/간암 Pancreatic Gallbladder Liver Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Chi KH, et al(2005), Combination of conformal radiotherpay and intratumoural injection of adoptive dendritic cell immunotherapy in refractory hepatoma, J Immunother, (2):129-35.
Dohnal AM, et al(2007), Phase I study of tumor Ag-loaded IL-12 secreting semi-mature DC for the treatment of pediatric cancer, Cytotherapy, (8):755-70.
Iwashita Y, et al(2003), A phase I study of autologous dendritic cell-based immunotherapy for patients with unresectable primary liver cancer, Cancer Immunol Immunother, (3):155-61.
Morse M, et al(1999), A phase 1 study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic cultured dendritic cells in patients with metastatic malignancies expres, Clin Cancer Res, (6):1331-8.
Mazzolini G,et al(2005), Intratumoral injection of dendritic cells engineered to secrete interleukin-12 by recombinant adenovirus in patients with metastatic gastrointestinal carcinomas, J Clin Oncol, (5):999-1010.
Pecher G, et al(2002), Mucin gene (MUC1) transfected dendritic cells as vaccine: results of a phase I/II clinical trial, Cancer Immunol Immunother, (11-12):669-73.
Palmer DH, et al(2009), A phase II study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma, Hepatology, (1):124-32.
Schott M, et al(2001), Dendritic cell immunotherapy in a neuroendocrine pancreas carcinoma, Clin Endocrinol, (Oxf) (2):271-7.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 유방암 Breast Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Avigan D, et al(2004), Fusion cell vaccination of patients with metastatic breast and renal cancer induces immunological and clinical responses, Clin Cancer Res, (14):4699-708.
Brossart P, et al(2000), Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells, Blood, (9):3102-8.
Dees CE, et al(2004), Dendritic cells can be rapidly expanded ex vivo and safely administered in patients with metastatic breast cancer, Cancer Immunol Immunother, (9):777-85.
Homma S, et al(2005), Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12, Eur J Clin Invest, (4):279-86.
Katano M, et al(2005), Combination therapy with tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas, Anticancer Res, (6A):3771-6.
Kobayashi T, et al(2001), Regression of lymph node metastases by immunotherapy using autologous breast tumor-lysate pulsed dendritic cells: report of a case, Surg Today, (6):513-6.
Loveland BE, et al(2006), Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase I trial in patients with adenocarcinoma, Clin Cancer Res, (3 Pt 1):869-77.
Mayordomo JI, et al(2007), Results of a pilot trial of immunotherapy with dendritic cells pulsed with autologous tumor lysates in patients with advanced cancer. Tumori, (1):26-30.
Morse M, et al(1999), A phase 1 study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic cultured dendritic cells in patients with metastatic malignancies expressing carcinoembryonic antigen, Clin Cancer Res, (6):1331-8.
Park JW, et al(2007), Treatment with autologous antigen-presenting cells activated with the HER-2 based antigen Lapuleucel-T: results of a phase I study in immunologic and clinical activity in HER-2 overexpressing breast cancer, J Clin Oncol, (24):3680-7.
Pecher G. et al(2002), Mucin gene (MUC1) transfected dendritic cells as vaccine: results of a phase I/II clinical trial, Cancer Immunol Immunother, (11-12):669-73.
Svane IM, et al(2007), Vaccination with p53 peptide-pulsed dendritic cells is associated with disease stabilization in patients with p53 expressing advanced breast cancer; monitoring of serum YKL-40 and IL-6 as response biomarkers, Cancer Immunol Immunother, (9):1485-99.
Svane IM, et al(2004), Vaccination with p53-peptide-pulsed dendritic cells, of patients with advanced breast cancer: report from a phase I study, Cancer Immunol Immunother, (7):633-41.
Triozzi PL, et al(2000), Intratumoural injection of dendritic cells derived in vitro in patients with metastatic cancer, Cancer, (12):2646-54.
Vonderheide RH, et al(2004), Vaccination of cancer patients against telomerase induces functional antitumour CD8+ T Lymphocytes, Clin Cancer Res, (3):828-39.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 폐암 Lung Cancer 
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Chang GC, et al(2005), A pilot trial of vaccination with dendritic cells pulsed with autologous tumor cells derived from malignant pleural effusion in patients with late-stage lung carcinoma, Cancer, 103(4):763-71.
Fong L. et al(2001), Altered peptide ligand vaccination with Flt3 ligand expanded dendritic cells for tumor immunotherapy, Proc Natl Acad Sci U S A, (15):8809-14.
Hirschowitz EA, et al(2007), Immunization of NSCLC patients with antigen-pulsed immature autologous dendritic cells, Lung Cancer, (3):365-72.
Ishikawa A, et al(2005), A phase I study of α-galactosylceramide (KRN7000)-pulsed dendritic cells in patients with advanced and recurrent non-small cell lung cancer, Clin Cancer Res, (5):1910-7.
Itoh T, et al(2002), Immunotherapy of solid cancer using dendritic cells pulsed with the HLA-A24-restricted peptide of carcinoembryonic antigen, Cancer Immunol Immunother, (2):99-106.
Katano M, et al(2005), Combination therapy with tumor cell-pulsed dendritic cells and activated lymphocytes for patients with disseminated carcinomas, Anticancer Res, (6A):3771-6.
Loveland BE, et al(2006), Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase I trial in patients with adenocarcinoma, Clin Cancer Res, (3 Pt 1):869-77.
Mayordomo JI, et al(2007), Results of a pilot trial of immunotherapy with dendritic cells pulsed with autologous tumor lysates in patients with advanced cancer, Tumori, (1):26-30.
Morse MA, et al(2005), Phase I study of immunization with dendritic cells modified with fowlpox encoding carcinoembryonic antigen and costimulatory molecules, Clin Cancer Res, (8):3017-24.
Perroud MW Jr, et al(2011), Mature autologous dendritic cell vaccines in advanced non-small cell lung cancer: a phase I pilot study, J Exp Clin Cancer Res, :65.
Toungouz M, et al(2001), Transient expansion of peptide-specific lymphocytes producing IFN-gamma after vaccination with dendritic cells pulsed with MAGE peptides in patients with mage-A1/A3-positive tumors, J Leukoc Biol, (6):937-43.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 신장암 Kidney Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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ArroyoJC, et al(2004), Immune responses induced in vitro by CD16- and CD16+ monocyte-derived dendritic cells in patients with metastatic renal cell carcinoma treated with dendritic cells vaccines, J Clin Immunol, (1):86-96.
Dall'Oglio MF,et al(2011), Early experience with targeted therapy and dendritic cell vaccine in metastatic renal cell carcinoma after nephrectomy, Int Braz J Urol, (2):180-5; discussion 185-6.
Geiger J, et al(2001), Vaccination of pediatric solid tumour patients with tumour lysate-pulsed dendritic cells can expand specific T cells and mediate tumour regression, Cancer Res, (23):8513-9.
Holtl L, et al(2005), Allogeniec dendritic cell vaccination against metastatic renal cell carcinoma with or without cyclophosphamide, Cancer Immunol Immunother, (7):663-70.
Holtl L, et al(2002), Immunotherapy of metastatic renal cell carcinoma with tumour lysate-pulsed autologous dendritic cells, Clin Cancer Res, (11):3369-76.
Kim JH, et al(2007), Phase I/II study of immunotherapy using autologous tumor lysate-pulsed dendritic cells in patients with metastatic renal cell carcinoma, Clin Immunol, (3):257-67.
Kugler A, et al(2000), Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids, Nat Med, (3):332-6.
Mackall CL, et al(2008), A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas, Clin Cancer Res, (15):4850-8.
Mayordomo JI, et al(2007), Results of a pilot trial of immunotherapy with dendritic cells pulsed with autologous tumor lysates in patients with advanced cancer, Tumori, (1):26-30.
Marten A, et al(2003), Allogeneic dendritic cells fused with tumor cells: Pre clinical results and outcome of a clinical phase I/II trial in patients with metastatic renal cell carcinoma, Hum Gene Ther, (5):483-94.
Marten A, et al(2002), Therapeutic vaccination against metastatic renal cell carcinoma by autologous dendritic cells: preclinical results and outcome of a first clinical phase I/II trial. 2002, Cancer Immunol Immunother, (11-12):637-44.
Nair SK, et al(1999), Induction of carcinoembryonic antigen (CEA)-specific cytotoxic T-lymphocyte responses in vitro using autologous dendritic cells loaded with CEA peptide or CEA RNA in patients with metastatic malignancies expressing CEA, Int J Cancer, (1):121-4
Pandha H, et al(2004), Dendritic cell immunotherapy for urological cancers using cryopreserved allogeneic tumour lysate-pulsed cells: a phase I/II study, BJU Int, (3):412-8.
Su Z, et al(2003), Immunological and clinical responses in metastatic renal cancer patients vaccinated with tumour RNA-transfected dendritic cells, Cancer Res, (9):2127-33.
Wierecky J et al(2006), Immunologic and clinical responses after vaccinations with peptide-pulsed dendritic cells in metastatic renal cancer patients, Cancer Res, (11):5910-8.
Holtl L, et al(1999), Cellular and humoral immune responses in patients with metastatic renal cell carcinoma after vaccination with antigen pulsed dendritic cells, J Urol, (3):777-82.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 자궁/난소암 Uterine/Ovarian Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Loveland BE, et al(2006), Mannan-MUC1-pulsed dendritic cell immunotherapy: A phase I trial in patients with adenocarcinoma, Clin Cancer Res, (3 Pt 1):869-77.
Homma S, et al(2005), Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12, Eur J Clin Invest, (4):279-86.
Hernando JJ, et al(2002), Vaccination with autologous tumour antigen-pulsed dendritic cells in advanced gynecological malignancies: clinical and immunological evaluation of a phase I trial, Cancer Immunol Immunother, (1):45-52
Brossart P, et al(2000), Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells, Blood, (9):3102-8.
Morse M, et al(1999), A phase 1 study of active immunotherapy with carcinoembryonic antigen peptide (CAP-1)-pulsed, autologous human cultured dendritic cells in patients with metastatic cultured dendritic cells in patients with metastatic malignancies expres, Clin Cancer Res, (6):1331-8.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 전립선암 Prostate Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Barrou B, et al(2004), Vaccination of prostatectomized prostate cancer patients in biochemical relapse, with autologous dendritic cells pulsed with recombinant human PSA, Cancer Immunol Immunother, (5):453-60.
Burch PA, et al(2000), Priming tissue-specific cellular immunity in a phase I trial of autologous dendritic cells for prostate cancer, Clin Cancer Res, (6):2175-82.
Fuessel S et al(2006), Vaccination of hormone-refractory prostate cancer patients with peptide cocktail-loaded dendritic cells: results of a phase I clinical trial, Prostate, (8):811-21.
Fong L, et al(2001), Dendritic cell-based xenoantigen vaccination for prostate cancer immunotherapy, J Immunol, (12):7150-6.
L, et al(2001), Dendritic cells injected via different routes induce immunity in cancer patients, J Immunol, (6):4254-9.
Hildenbrand B, et al(2007), Immunotherapy of patients with hormone-refractory prostate carcinoma pre-treated with interferon-gamma and vaccinated with autologous PSA-peptide loaded dendritic cells--a pilot study, Prostate, (5):500-8.
Heiser A, et al(2002), Autologous dendritic cells transfected with prostate-specific antigen RNA stimulate CTL responses against metastatic prostate tumors, J Clin Invest, (3):409-17.
Lawrence Fong et al(2001) Dendritic Cell-Based Xenoantigen Vaccination for Prostate Cancer Immunotherapy, J Immunol, (12):7150-6.
LJ Mu, et al(2005), Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients, Br J Cancer, (7):749-56.
Lodge PA, et al(2000), Dendritic cell-based immunotherapy of prostate cancer: immune monitoring of a phase II clinical trial, Cancer Res, (4):829-33.
Murphy GP, et al(1999), Infusion of dendritic cells pulsed with HLA-A2-specific prostate-specific membrane antigen peptides: a phase 2 prostate cancer vaccine trial involving patients with hormone-refractory metastatic disease, (1):73-8.
Murphy GP, et al(2000), Higher dose and less frequent dendritic cell infusions with PSMA peptides in hormone-refractory metastatic prostate cancer patients, Prostate, (1):59-62.
Murphy GP, et al(1999), Phase II prostate cancer vaccine trial: report of a study involving 37 patients with disease recurrence following primary treatment, Prostate, (1):54-9.
Pandha H, et al(2004), Dendritic cell immunotherapy for urological cancers using cryopreserved allogeneic tumour lysate-pulsed cells: a phase I/II study, BJU Int, (3):412-8.
Small EJ, et al(2000), Immunotherapy of hormone-refractory prostate cancer with antigen-loaded dendritic cells, J Clin Oncol, (23):3894-903.
Thomas-Kaskel AK, et al(2006), Vaccination of advanced prostate cancer patients with PSCA and PSA peptide-loaded dendritic cells induces DTH responses that correlate with superior overall survival, Int J Cancer, (10):2428-34.
Tjoa BA, et al(1999), Follow-up evaluation of a phase II prostate cancer vaccine trial, Prostate, (2):125-9.
Vonderheide RH, et al(2004), Vaccination of cancer patients against telomerase induces functional antitumour CD8+ T Lymphocytes, Clin Cancer Res, (3):828-39.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 소아암 Childhood Cancer
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Dohnal AM, et al(2007), Phase I study of tumor Ag-loaded IL-12 secreting semi-mature DC for the treatment of pediatric cancer, Cytotherapy, (8):755-70.
Dagher R, et al(2002), Pilot trial of tumour-specific peptide vaccination and continuous infusion interleukin-2 in patients with recurrent ewing sarcoma and alveolar rhabdomyosarcoma: a inter-institute NIH study, Med Pediatr Oncol, (3):158-64
Geiger J, et al(2001), Vaccination of pediatric solid tumour patients with tumour lysate-pulsed dendritic cells can expand specific T cells and mediate tumour regression, Cancer Res, (23):8513-9.
Geiger J, et al(2000), Treatment of solid tumours in children with tumour-lysate-pulsed dendritic cells, Lancet, (9236):1163-5.
Mackall CL, et al(2008) A pilot study of consolidative immunotherapy in patients with high-risk pediatric sarcomas, Clin Cancer Res, (15):4850-8.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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 악성흑색종 Malignant melanoma
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Akiyama Y, et al(2005), Clinical pesponse in Japanese metastatic melanoma patients treated with peptide cocktail-pulsed dendritic cells, J Transl Med, (1):4.
Andersen MH, et al(2001), Induction of systemic CTL responses in melanoma patients by dendritic cell vaccination: cessation of CTL responses is associated with disease progression, Int J Cancer, (6):820-4.
Banchereau J, et al(2001), Immune and clinical responses in patients with metastatic melanoma to CD34(+) progenitor-derived dendritic cell vaccine, Cancer Res, (17):6451-8.
Banchereau J, et al(2005), Immune and clinical outcomes in patients with stage IV melanoma vaccinated with peptide-pulsed dendritic cells from CD34+ progenitors and activated with type I interfereon, J Immunother, (5):505-16.
Bedrosian I, et al(2003), Intranodal administration of peptide-pulsed mature dendritic cell vaccines results in superior CD8+ T-cell function in melanoma patients, J Clin Oncol, (20):3826-35.
Cornforth A,et al(2011), Autologous peripheral blood mononuclear cell recognition of autologous proliferationg tumor cells in the context of a patient-specific vaccine trial, J Biomed Biotech, Epub. Chang AE, et al(2002), A Phase I Trial of Tumor Lysate-pulsed Dendritic Cells in the Treatment of Advanced Cancer, Clin Cancer Res, (4):1021-32.
De Vries IJ, et al(2005), Immunomonitoring tumor-specific T cells in delayed-type hypersensitivity skin biopsies after dendritic cell vaccination correlates with clinical outcome,J Clin Oncol, (24):5779-87.
Di Nicola M, et al(2004), Boosting T cell-mediated immunity to tyrosinase by vaccinia virus-transduced, CD34+ derived dendirtic cell vaccination: A phase I trialin metastatic melanoma, Clin Cancer Res, (16):5381-90
De Vries IJ, et al(2003), Maturation of dendritic cells is a prerequisite for inducing immune responses in advanced melanoma patients, Clin Cancer Res, (14):5091-100.
Escobar A, et al(2005), Dendritic cell immunizations alone or combined with low doses of interleukin-2 induce specific immune responses in melanoma patients, Clin Exp Immunol , (3):555-68.
Fay JW, et al(2006), Long-term outcomes in patients with metastatic melanoma vaccinated with melanoma peptide-pulsed CD34+ progenitor-derived dendritic cells. Cancer Immunol Immunother, Cancer Immunol Immunother, (10):1209-18.
Homma S, et al(2005), Cancer immunotherapy by fusions of dendritic and tumour cells and rh-IL-12, Eur J Clin Invest, (4):279-86.
Hersey P, et al(2004), Phase I/II study of treatment with dendritic cell vaccines in patients with disseminated melanoma, Cancer Immunol Immunother, (2):125-34.
Hersey P, et al(2008), Phase I/II study of treatment with matured dendritic cells with or without low dose IL-2 in patients with disseminated melanom, Cancer Immunol Immunother, (7):1039-51.
Jonuleit H, et al(2001), A comparison of two types of dendritic cell as adjuvants for the induction of melanoma-specific T-cell responses in humans following intranodal injection, Int J Cancer, (2):243-51.
Lopez MN. Lopez et al(2009), Prolonged Survival of Dendritic Cell?Vaccinated Melanoma Patients Correlates With Tumor-Specific Delayed Type IV Hypersensitivity Response and Reduction of Tumor Growth Factor β-Expressing T Cells, J Clin Oncol, (6):945-52.
Linette GP, et al(2005), Immunization using autologous dendritic cells pulsed with the melanoma-associated antigen gp100-derived G280-9V peptide elicits CD8+ immunity, Clin Cancer Res, (21):7692-9.
Mackensen A, et al(2000), Phase I study in melanoma patients of a vaccine with peptide-pulsed dendritic cells generated in vitro from CD34(+) hematopoietic progenitor cells, Int J Cancer, (3):385-92.
Mayordomo JI, et al(2007), Results of a pilot trial of immunotherapy with dendritic cells pulsed with autologous tumor lysates in patients with advanced cancer, Tumori, (1):26-30.
Nagayama H, et al(2003), Results of a phase I clinical study using autologous tumour lysate-pulsed monocyte-derived mature dendritic cell vaccinations for stage IV malignant melanoma patients combined with low dose interleukin-2, Melanoma Res, (5):521-30.
Nakai N, et al(2006), Vaccination of Japanese patients with advanced melanoma with peptide, tumor lysate or both peptide and tumor lysate-pulsed mature, monocyte-derived dendritic cells, J Dermatol, (7):462-72.
Ridolfi L,et al(2010), Unexpected high response rate to traditional therapy after dendritic cell-based vaccine in advanced melanoma: update of clinical outcome and subgroup analysis, Clin Dev Immunol, 2010;2010:504979, Epub. Ribas A,et al(2010), Multicenter phase II study of matured dendritic cells pulsed with melanoma cell line lysates in patients with advanced melanoma, J Transl Med, :89.
Ridolfi R, et al(2006), Improved overall survival in dendritic cell vaccination-induced immunoreactive subgroup of advanced melanoma patients, J Transl Med, 4:36
Schuler-Thurner B, et al(2002), Rapid induction of tumor-specific type1 T helper cells in metastatic melanoma patients by vaccination with mature, cryopreserved, peptide-loaded monocyte-derived dendritic cells, J Exp Med, (10):1279-88.
Slingluff CL Jr, et al(2003), Clinical and Immunologic results of a randomized phase II trial of vaccination using four melanoma peptides either administered in granulocyte-macrophage colony-stimulating factor in adjuvant or pulsed on dendritic cells, J Clin Oncol, (21):4016-26.
Salcedo M, et al(2006), Vaccination of melanoma patients using dendritic cells loaded with an allogeneic tumor cell lysate, Cancer Immunol Immunother, (7):819-29.
Schuler-Thurner B, et al(2000), Mage-3 and influenza-matrix peptide-specific cytotoxic T cells are inducible in terminal stage HLA-A2.1+ melanoma patients by mature monocyte-derived dendritic cells, J Immunol, (6):3492-6. Toungouz M, et al(2001), Transient expansion of peptide-specific lymphocytes producing IFN-gamma after vaccination with dendritic cells pulsed with MAGE peptides in patients with mage-A1/A3-positive tumors, J Leukoc Biol, (6):937-43.
Trefzer U, et al(2000), Hybrid cell vaccination for cancer immune therapy: first clinical trial with metastatic melanoma, Int J Cancer, (5):618-26.
Triozzi PL, et al(2000), Intratumoural injection of dendritic cells derived in vitro in patients with metastatic cancer, Cancer, (12):2646-54.
Trefzer U, et al(2004), Vaccination with hybrids of tumor and dendritic cells induces tumor-specific T-cell and clinical responses in melanoma stage III and IV patients, Int J Cancer, (5):730-40.
Trefzer U, et al(2005), Tumour-dendritic hybrid cell vaccination for the treatment of patients with malignant melanoma: immunological effects and clinical results, Vaccine, (17-18):2367-73.
von Euw EM, et al(2008), A phase I clinical study of vaccination of melanoma patients with dendritic cells loaded with allogeneic apoptotic/necrotic melanoma cells. Analysis of toxicity and immune response to the vaccine and of IL-10 -1082 promoter genotype as predictor of disease progression, J Transl Med, :6.
Vilella R, et al(2004), Pilot study of treatment of biochemotherapy-refractory stage IV melanoma patients with autologous dendritic cells pulsed with a heterogenous melanoma cell line lysate, Cancer Immunol Immunother, (7):651-8.
Wei Y, et al(2006) Dendritoma vaccination combined with low dose interleukin-2 in metastatic melanoma patients induced immunological and clinical responses, Int J Oncol, (3):585-93.
       
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 백혈병/형질세포종양 Leukemia/plasma Cell Tumor
       
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Curti A, et al(2007), Phase I / II clinical trial of sequential subcutaneous and intravenous delivery of dendritic cell vaccination for refractory multiple myeloma using patient-specific tumour idiotype protein or idiotype (VDJ)-derived class I-restricted peptides, Br J Haematol, (3) :415-24.
Cull C, et al(1999), Generation of anti-ideotype immune responses following vaccination with ideotype-protein pulsed dendritic cells in myeloma, Br J Haematol, (3) :648-55.
Kitawaki T.et al(2011), A phase I / IIa clinical trial of immunotherapy for elderly patients with acute myeloid leukaemia using dendritic cells co-pulsed with WT1 peptide and zoledronate, Br J Haematol, (6) : 796 - 9.
Lim SH, et al(1999), Idiotypic protein-pulsed dendritic cell vaccination in multiple myeloma, Int J Cancer, (2) :215-22.
Ossenkoppele GJ, et al(2003), Vaccination of chronic myeloid leukemia with autologous in vitro cultured leukemic dendritic cells, Leukemia, (7) :1424-6.
Reichardt VL, et al(2003), Idiotype vaccination of multiple myleoma patients using monocyte-derived dendritic cells, Haematologica, (10) :1139-49.
Reichardt VL, et al(1999), Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma - a feasibility study, Blood, (7) :2411-9.
Titzer S, et al(2000), Vaccination of multiple myeloma patients with idiotype-pulsed dendritic cells : immunological and clinical aspects, Br J Haematol, (4) :805-16.
Viggo F. et al(2010), Van Tendelooa at el.Induction of complete and molecular remissions in acute myeloid leukemia by Wilms 'tumor 1antigen-targeted dendritic cell vaccination, Proc Natl Acad Sci USA, (31) : 13824-9.
Yi Q, et al(2002), Optimizing dendritic cell-based immunotherapy in multiple myeloma, Br J Haematol, (2) :297-305.
       
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 악성림프종 Malignant Lymphoma
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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Hus I, et al(2005), Allogeneic dendritic cells pulsed with tumor lysates or apoptotic bodies as immunotherapy for patients with early-stage B-cell chronic lymphocytic leukemia, Leukemia, (9) :1621-7.
Hsu FJ, et al(1996), Vaccination of patients with B-cell lymphoma using autologous antigen-pulsed dendritic cells, Nat Med, (1) :52-8.
Maier T, et al(2003) Vaccination of patients with cutaneous T cell lymphoma using intranodal injection of autologous tumour-lysate-pulsed dendritic cell, Blood, (7) :2338-44.
Timmerman J. et al(2002), Idiotype-pulsed dendritic cell vaccination for B-cell lymphoma : clinical and immune responses in 35 patients, Blood, (5) :1517-26.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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세계가 인정하는 수지상세포백신치료의 논문발표
       
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수지상세포백신치료의 임상연구는 미국, 유럽 세계유명학회지 등에 게재 되었고 현재도 지속적으로 꾸준하게 임상논문이 발표되고 있습니다. 일본 세렌크리닉병원그룹의 의료진과 연구진은 항상 암 치료에 있어 매일매일 연구에 몰두하며 보다 더 진보된 암 치료에 매진하고 있습니다.
       
위・아래 삭제 복제 복제전송 텍스트기본스타일
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2015년
       
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발표월일학회명개최지발표제목
10월21일World Journal of Gas
troenterology
동경자혜회
의과대학
진행성 췌장암에 대한 수지상세포백신요법과
항암제 병원에 의한 예후예측 인자의 검토
03월09일Cancer Science게이오대학진행성 췌장암에 대한 WT1펩티드를 사용한 수지상세포
백신요법의 완수성과 면역반응의 증가
01월07일World Journal of Sur
gical Oncology
영국Therapeutic effect of intratumoral injections of
dendritic cell for locallyrecurrent gastric cancer,
국소 재발 위암에 관한 수지상백신요법의 종양 내 국소투여의 사례보고
       
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발표

월일

학회명

개최지

발표제목

10월

21일

World Journal

 of 

Gastroenterology

동경자혜회

의과대학

진행성 췌장암에 대한 수지상세포백신요법과 항암제 병원에 의한 예후예측 인자의 검토

03월

09일

Cancer Science

게이오

대학

진행성 췌장암에 대한 WT1펩티드를 사용한 수지상세포 백신요법의 완수성과 면역반응의 증가

01월

07일

World Journal 

of 

Surgical Oncology

영국

Therapeutic effect of intratumoral injections of dendritic cell for locallyrecurrent gastric cancer, 국소 재발 위암에 관한 수지상백신요법의 종양 내 국소투여의 사례보고